Effect of continuous positive airway pressure therapy on recurrence of atrial fibrillation after pulmonary vein isolation in patients with obstructive sleep apnea: A randomized controlled trial
Rattachement africain : no. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Obstructive sleep apnea (OSA) is associated with atrial fibrillation (AF). Whether treatment with continuous positive airway pressure (CPAP) reduces AF recurrence after catheter ablation with pulmonary vein isolation (PVI) is unknown. OBJECTIVE: The purpose of this study was to assess the effect of CPAP treatment on the recurrence and burden of AF after PVI in patients with OSA. METHODS: We randomized patients with paroxysmal AF and an apnea-hypopnea index (AHI) ≥15 events/hour to treatment with CPAP or standard care. Heart rhythm was monitored by an implantable loop recorder. AF recurrence after PVI was defined as any episode of AF lasting >2 minutes after a 3-month blanking period. RESULTS: PVI was performed in 83 patients. Thirty-seven patients were randomized to CPAP treatment and 46 patients to standard care. The AHI was reduced from 26.7 ± 14 events/hour to 1.7 ± 1.3 events/hour at follow-up in the CPAP group (P = .001). A total of 57% of patients in both the CPAP group and the standard care group had at least 1 episode of AF 3-12 months after PVI (P for difference = 1). AF burden after ablation was reduced in both groups, with no between-group difference (P = .69). CONCLUSION: In patients with paroxysmal AF and OSA, treatment with CPAP did not further reduce the risk of AF recurrence after ablation. PVI considerably reduced the burden of AF in OSA patients, without any difference between groups.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Effect of continuous positive airway pressure therapy on recurrence of atrial fibrillation after pulmonary vein isolation in patients with obstructive sleep apnea: A randomized controlled trial
- Date Crossref
- 01/09/2022
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Oslo University Hospital Department of Cardiology pays non établi dans la noticeÉtablissement de santé
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University of Oslo KG Jebsen Center for Cardiac Research pays non établi dans la noticeUniversité ou école supérieure
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Norwegian University of Science and Technology pays non établi dans la noticeUniversité ou école supérieure
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St Olav's University Hospital pays non établi dans la noticeÉtablissement de santé
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Lovisenberg Diakonale Høgskole pays non établi dans la noticeUniversité ou école supérieure
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Faculty of Medicine Institute of Clinical Medicine pays non établi dans la noticeUniversité ou école supérieure
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St. Olavs University Hospital Department of Thoracic Medicine pays non établi dans la noticeUniversité ou école supérieure
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Department of Otorhinolaryngology pays non établi dans la noticeOrganisation à but non lucratif
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St. Olav's University Hospital Department of Cardiology pays non établi dans la noticeUniversité ou école supérieure
Department of Cardiology — Oslo University Hospital, KG Jebsen Center for Cardiac Research — University of Oslo et Norwegian University of Science and Technology, avec 6 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.