Direct Oral Anticoagulants: Drug Selection by Means of the SOJA Method

Le résumé fourni par la source

MethodsThe SOJA method is a model for rational drug selection.The relevant selection criteria for a certain group of drugs are defined and judged by a panel of experts [i.e. the authors of the present article].The more important a selection criterion is considered, the higher the relative weight that is given to that criterion.The ideal properties for each selection criterion are determined and each drug is scored as a percentage of the relative weight for all selection criteria.The criteria, which were used in the present SOJA method and the weighting of the authors are presented in Table 3.A Medline search was performed, as well as a search for studies in the Cochrane library.As well as these searches, the references of review articles on this subject were obtained and incorporated in the analysis when appropriate.The manuscript was sent to the pharmaceutical companies for a check on scientific completeness and correctness, as well as for addition of any relevant new information to be included in the manuscript.The relative weights of the selection criteria and the ultimate judgement of the drugs were not discussed with the companies; this was the responsibility of the authors.The drugs with the highest total score are most suitable for formulary inclusion [1].The following drugs were included in the analysis:

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.