Treatment of localized renal cell cancer

Résumé fourni par la source

The incidence of localized renal cell carcinoma (RCC) has increased due to the widespread use of abdominal imaging, often for unrelated conditions. Despite improved understanding of the natural history of slow growth in many tumours and the impact of ageing and co-morbidities on patient survival, RCC is still the most lethal of genitourinary cancers and surgery remains the mainstay of treatment. Localized RCC is defined as stages T1-2 N0 M0. The relatively safe needle core biopsy is increasingly used, especially for small renal masses (SRMs), as we now know that up to 30% are benign and that RCC subtypes differ in biology and behaviour. Radical nephrectomy, either performed by open or laparoscopic technique, is indicated for stage T2 tumours or when partial nephrectomy (PN) is not believed to be feasible.

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