ACCURACY AND SAFETY OF LOWER GI EUS-GUIDED FNA/FNB: A RETROSPECTIVE SINGLE-CENTER STUDY

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Aims The aim was to analyze the performance characteristics and safety of EUS-guided fine-needle aspiration/fine needle biopsy (FNA/FNB) via the lower GI tract. Methods Records of 100 patients who were referred for lower GI EUS at a tertiary center between 2013 and 2020 were retrospectively reviewed. We evaluated EUS FNA/FNB performance by comparing EUS tissue diagnoses with the final diagnosis (obtained via resection / long term follow-up). Results 100 patients underwent lower GI EUS, of which 36 were intended as EUS FNA/FNB. In one patient, the lesion was not visible at EUS. In the remaining 35 patients the lesion was sampled. The most frequent location for EUS FNA/FNB was in the rectum (13/35). The majority of lesions were extraluminal (18/35) i.e. not visible endoscopically, the remainder were subepithelial. There were three mild complications (pain x 2, bleeding). The sensitivity, specificity, positive predictive value and accuracy of lower GI EUS-FNA/FNB was 93.0%, 71.4%, 93.0%, 88.6% respectively. The EUS FNA/FNB resulted in a change in the pre-EUS diagnosis in 15/35 cases. Conclusions Lower GI EUS-FNA/FNB is an accurate and safe technique. It can be considered for any lesion requiring tissue sampling that is related to the lower GI tract. Publication History Article published online: 14 April 2022 © 2022. European Society of Gastrointestinal Endoscopy. All rights reserved. Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany

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