Safety of SARS-CoV-2 vaccination in people with a history of acute myocarditis

Le résumé fourni par la source

Abstract Funding Acknowledgements Type of funding sources: None. Background SARS-CoV-2 is a global health issue. Rare cases of myocarditis following SARS-CoV-2 vaccination have been reported in the literature. Purpose There is a lack of data regarding the risk of myocarditis recurrence after SARS-CoV-2 vaccination in patients with a history of myocarditis. We hypothesized that SARS-CoV-2 vaccination did not increase the risk of myocarditis recurrence in patients with prior history of myocarditis. Methods We selected all the patients hospitalized in our hospital for the last five years (from January 2016 to June 2021) with a diagnosis of acute myocarditis. Patients were contacted with a phone call to answer a standardized questionnaire on their vaccination status and events related to the vaccination to assess the safety of SARS-CoV2 vaccination in this population. Data concerning their vital status was collected in their centralized medical file. Results We enrolled 142 patients with prior history of confirmed acute myocarditis. 16 patients refused vaccination, 12 of them had a fear of myocarditis recurrence. There were no serious adverse events in the vaccinated group. Conclusion We showed that SARS-CoV-2 vaccination in patients with prior history of acute myocarditis is not associated with a risk of myocarditis recurrence or serious side effects. These results provide reassuring data that may incite patients with prior history of myocarditis to get vaccinated against SARS-CoV-2.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.