Pain Management in Chronic Kidney Disease

Le résumé fourni par la source

End-stage renal disease (ESRD) is a common disorder leading to uncontrolled symptoms in patients requiring palliative care. Selection of analgesics for patients with chronic kidney disease is complex because consideration must be given to avoid further nephrotoxicity and prevent adverse drug events due to accumulation of the drug or its metabolites. Additionally, uremic neuropathy may further complicate treatment plans. Nonsteroidal anti-inflammatory drugs (NSAIDs), in most cases, should be avoided and the clinician should consider opioids such as fentanyl, methadone, or buprenorphine in those patients with uncontrolled pain of moderate or higher severity.

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