The role of EUS elastography-guided fine needle biopsy in the histological diagnosis of solid pancreatic lesions: A prospective exploratory study
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Le résumé fourni par la source
Abstract AimsThis study aimed to evaluate the feasibility and efficacy of Endoscopic ultrasound elastography-guided fine needle biopsy (EUS-EG-FNB) for the diagnosis of pancreatic mass lesions.MethodsEUS-EG images were classified into heterogeneous and homogeneous groups. For the heterogeneous group, EUS-FNB was separately performed in both hard areas and soft areas. Only samples obtained during the first two passes (hard/soft areas) were used to compare the diagnostic accuracy as well as the quality and quantity of the specimens. We investigated the association of EUS-EG findings using strain histogram analysis with the histological findings.ResultsFifty-five patients were enrolled including 25 patients with heterogeneous group. The homogeneous group had significantly lower mean strain value (hard) lesions. The adequate sampling rates from hard and soft areas were 88% and 92%, respectively (P=0.6374). Comparison of the diagnostic accuracy and the quality and quantity of the histological core between hard and soft areas showed no significant differences. In pancreatic adenocarcinoma cases, the proportion of fibrous stroma in the core tissue was significantly correlated with the elasticity of the region. (R2=0.1226: P=0.0022) ConclusionEUS-EG may reflect tissue composition in pancreatic tumors, however, EUS-EG did not affect either the quality and quantity of the tissues obtained.(Clinical Trial Registry No. UMIN-000033073)
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- The role of EUS elastography-guided fine needle biopsy in the histological diagnosis of solid pancreatic lesions: A prospective exploratory study
- Date Crossref
- 31/03/2022
- Éditeur
- Research Square Platform LLC
- Type
- posted-content
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Nagoya University pays non établi dans la noticeUniversité ou école supérieure
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Nagoya University Hospital pays non établi dans la noticeÉtablissement de santé
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Kashiwa Municipal Hospital pays non établi dans la noticeÉtablissement de santé
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Fujita Health University pays non établi dans la noticeUniversité ou école supérieure
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The Nakamura Hajime Eastern Institute pays non établi dans la noticeStructure de recherche
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Nakatsugawa Municipal Hospital pays non établi dans la noticeÉtablissement de santé
Nagoya University, Nagoya University Hospital et Kashiwa Municipal Hospital, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.