Clinical Tick-Borne Encephalitis in a Roe Deer (Capreolus capreolus L.)
Rattachement africain : it. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Tick-borne encephalitis virus (TBEV) is the causative agent of tick-borne encephalitis (TBE), a severe zoonosis occurring in the Palearctic region mainly transmitted through Ixodes ticks. In Italy, TBEV is restricted to the north-eastern part of the country. This report describes for the first time a case of clinical TBE in a roe deer (Capreolus capreolus L.). The case occurred in the Belluno province, Veneto region, an area endemic for TBEV. The affected roe deer showed ataxia, staggering movements, muscle tremors, wide-base stance of the front limbs, repetitive movements of the head, persistent teeth grinding, hypersalivation and prolonged recumbency. An autopsy revealed no significant lesions to explain the neurological signs. TBEV RNA was detected in the brain by real-time RT-PCR, and the nearly complete viral genome (10,897 nucleotides) was sequenced. Phylogenetic analysis of the gene encoding the envelope protein revealed a close relationship to TBEV of the European subtype, and 100% similarity with a partial sequence (520 nucleotides) of a TBEV found in ticks in the bordering Trento province. The histological examination of the midbrain revealed lymphohistiocytic encephalitis, satellitosis and microgliosis, consistent with a viral etiology. Other viral etiologies were ruled out by metagenomic analysis of the brain. This report underlines, for the first time, the occurrence of clinical encephalitic manifestations due to TBEV in a roe deer, suggesting that this pathogen should be included in the frame of differential diagnoses in roe deer with neurologic disease.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Clinical Tick-Borne Encephalitis in a Roe Deer (Capreolus capreolus L.)
- Date Crossref
- 31/01/2022
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Istituto Zooprofilattico Sperimentale delle Venezie pays non établi dans la noticeÉtablissement de santé
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OIE Collaborating Centre for Diseases at the Animal/Human Interface pays non établi dans la noticeInstitution
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U.O. Ecopathology SCT2-Belluno pays non établi dans la noticeInstitution
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Laboratory for Viral Genomics and Trascriptomics pays non établi dans la noticeStructure de recherche
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Laboratory of Parasitology Micology and Sanitary Enthomology pays non établi dans la noticeStructure de recherche
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Histopathology Laboratory pays non établi dans la noticeStructure de recherche
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Laboratory for Viral Emerging Zoonoses pays non établi dans la noticeStructure de recherche
Istituto Zooprofilattico Sperimentale delle Venezie, OIE Collaborating Centre for Diseases at the Animal/Human Interface et U.O. Ecopathology SCT2-Belluno, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.