Intravenous versus subcutaneous delivery of biotherapeutics in IBD: an expert’s and patient’s perspective
Rattachement africain : lt, rs, hu, ro, hr, ee, lv, bg, si. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Several biologic treatments are available in addition to intravenous also in subcutaneous form for treatment of chronic diseases. Benefits of the subcutaneous application of drugs include self-administration by the patient, shorter time of application process with less infusion related adverse events and consequently lower healthcare costs. With appropriate education and support patients are able to administer their treatments at home. This leads to improvement of quality of life, reduction of time needed to travel to the healthcare institution and consequently also reduces costs also for the patient.Over one million residents in the USA and 2.5 million in Europe are estimated to have inflammatory bowel disease (IBD), with substantial costs for health care. These estimates do not factor in the 'real' price of IBD, which can impede career aspirations, instil social stigma and impair quality of life in patients.The Virtual Community Meeting, which offered an exchange of experience and opinions from healthcare professionals who are active in treating IBD, and patients with this chronic disease, revealed in-depth arguments and answers to some essential questions: which patients prefer subcutaneous over intravenous dosing; which patients continue to favour intravenous infusions; what are the limitations regarding both applications; what is the patient's role in therapeutical decision-making and how does IBD affect the patient's work, finances and quality of life? The aim of this article is to discuss the differences between subcutaneous and intravenous dosing from the health-economic, scientific, and personal perspectives.The meeting offered strong confirmation that most of the patients and healthcare professionals prefer subcutaneous over intravenous drug administration but emphasise the management of risks associated with treatment compliance. Patient education provided by the IBD team in this regard is mandatory. Quality of life of patients is poorer during active disease, but the findings that it can improve over time, including as a result of home- or self-administration of biologics, may be encouraging for individuals with this chronic disease.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Intravenous versus subcutaneous delivery of biotherapeutics in IBD: an expert’s and patient’s perspective
- Date Crossref
- 01/12/2021
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Lithuanian University of Health Sciences Gastroenterology clinic pays non établi dans la noticeUniversité ou école supérieure
-
University Hospital Medical Center Bezanijska kosa pays non établi dans la noticeÉtablissement de santé
-
University of Szeged Department of Gastroenterology pays non établi dans la noticeUniversité ou école supérieure
-
Institutul Clinic Fundeni pays non établi dans la noticeÉtablissement de santé
-
University Hospital Centre Zagreb pays non établi dans la noticeÉtablissement de santé
-
Tartu University Hospital Division of Gastroenterology pays non établi dans la noticeÉtablissement de santé
-
University of Tartu pays non établi dans la noticeUniversité ou école supérieure
-
Pauls Stradiņš Clinical University Hospital pays non établi dans la noticeÉtablissement de santé
-
University Hospital St. Ivan Rilski pays non établi dans la noticeÉtablissement de santé
-
University of Ljubljana pays non établi dans la noticeUniversité ou école supérieure
-
Ljubljana University Medical Centre pays non établi dans la noticeÉtablissement de santé
-
University Hospital Medical Center Zvezdara Department of Gastroenterology pays non établi dans la noticeUniversité ou école supérieure
Gastroenterology clinic — Lithuanian University of Health Sciences, University Hospital Medical Center Bezanijska kosa et Department of Gastroenterology — University of Szeged, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.