What are the determinants of childhood infections in India’s peri-urban slums? A case study of eight cities
Rattachement africain : gb, sg, us, in. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Respiratory Tract Infections (RTIs) and Gastro-Intestinal (GI) infections are the leading causes of child mortality and morbidity. This study investigates the associations between the individual, household and slum-level determinants of children's health and vulnerability to RTIs and GI infections in peri-urban slums in India; an area of research interest at the Childhood Infections and Pollution Consortium. METHODS: The 2015-16 Indian National Family Health Survey was used for data analysis on children aged 0-5 years. NFHS-4 includes data on slums in eight Indian cities, including Delhi, Meerut, Kolkata, Indore, Mumbai, Nagpur, Hyderabad, Chennai. The outcome variables, having fever and cough (FeCo) and diarrhoea in the last two weeks, were used to define the phenotype of infections; for this analysis fever and cough were measures of RTIs and diarrhoea was used to measure GI infections. Exposures considered in this study include variables at the individual, household and slum level and were all informed by existing literature. Multilevel models were used to estimate the association between exposures and outcomes variables; a prior of Cauchy distribution with a scale of 2.5 was selected when building the multilevel logistic models. RESULTS: The total sample size of the number of children included in the analysis was n = 1,424. Data was imputed to account for missingness, and the original and imputed sample showing similar distributions. Results showed that diarrhoea and FeCo were both found to be more present in younger children than older children by a few months. In fixed effects, the odds of developing FeCo were higher if the mother perceives the child was born smaller than average (AOR 4.41, 1.13-17.17, P<0.05) at individual level. On the other hand, the odds of the diarrhoea outcome were lower if the child was older (AOR 0.97, 0.96-0.98, P<0.05) at individual level, and household's water source was public tap or standpipe (AOR 0.54, 0.31-0.96, P<0.05) at household level. CONCLUSION: The determinants of health, both social and related to health care, at all levels demonstrated linkages to child morbidity in RTIs and GI infections. The empirical evidence highlights the need for contextualised ideas at each level, including one health approach when designing interventions to improve child health.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- What are the determinants of childhood infections in India’s peri-urban slums? A case study of eight cities
- Date Crossref
- 15/10/2021
- Éditeur
- Public Library of Science (PLoS)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Great Ormond Street Hospital pays non établi dans la noticeÉtablissement de santé
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University of Oxford Nuffield Department of Population Health pays non établi dans la noticeUniversité ou école supérieure
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GlobalFoundries (Singapore) pays non établi dans la noticeEntreprise
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University College London Department of Epidemiology and Public Health pays non établi dans la noticeUniversité ou école supérieure
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Brown University pays non établi dans la noticeUniversité ou école supérieure
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Whittington Health NHS Trust pays non établi dans la noticeÉtablissement de santé
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Columbia University pays non établi dans la noticeUniversité ou école supérieure
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London International Development Centre pays non établi dans la noticeInstitution
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Public Health Foundation of India pays non établi dans la noticeOrganisation à but non lucratif
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Aceso Global Health Consultants PTE Ltd. pays non établi dans la noticeEntreprise
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UCL Great Ormond Street Institute of Child Health Policy and Practice pays non établi dans la noticeStructure de recherche
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Bartlett School of Construction and Project Management Engineering for International Development Centre pays non établi dans la noticeUniversité ou école supérieure
Great Ormond Street Hospital, Nuffield Department of Population Health — University of Oxford et GlobalFoundries (Singapore), avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.