ElasticBLAST: Using the power of the cloud to speed up science

Le résumé fourni par la source

With the advent of faster and cheaper sequencing technologies, there exist ever larger amounts of sequence data to analyze. The Basic Local Alignment Search Tool (BLAST) is a core component of sequence analysis, though analyzing large volumes of sequence data remains a challenge, primarily because of computational demands. In order to leverage the offerings of cloud service providers to address the increased demands of today’s sequence analysis, we developed ElasticBLAST. ElasticBLAST is a cloud-based implementation of BLAST designed to speed up searching and aligning large amounts of nucleotide and protein sequences against NCBI or user-provided BLAST databases. Adhering to an Open Source Philosophy, the source code and documentation for ElasticBLAST are freely available on Github. The sequence databases that ElasticBLAST operates on are also freely available on the National Center for Biotechnology Information (NCBI)'s FTP site, the Registry of Open Data at AWS, and the Google Cloud Platform. This research was supported by the Intramural Research Program of the National Library of Medicine at the NIH

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