Nature and treatment outcomes of bleeding post‐bulbar duodenal ulcers
Rattachement africain : jp. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Although post-bulbar duodenal ulcers (PBDUs) could become a source of upper gastrointestinal bleeding, the whole picture of the disease is unknown. We compared the characteristic features and treatment outcomes after endoscopic hemostasis between PBDUs and bulbar duodenal ulcers (BDUs). METHODS: Data on duodenal ulcers with evidence of endoscopically-active bleeding were extracted from the data that were retrospectively collected from 12 institutes in Japan between 2011 and 2018. Rebleeding and in-hospital mortality were compared between patients with PBDUs and those with BDUs by logistic regression analyses. RESULTS: Among 468 consecutive patients with bleeding duodenal ulcers, 96 (20.5%) had endoscopically-confirmed PBDUs. PBDUs were more frequently observed in patients with a poor general condition in comparison to BDUs. The rates of rebleeding and in-hospital mortality in patients with PBDUs were approximately three times higher than those in patients with BDUs (PBDU vs. BDU: 29.2% vs. 10.2% [P < 0.0001] and 14.6% vs. 5.1% [P = 0.0029], respectively). Although the high in-hospital mortality in PBDUs could be explained, to a lesser extent, by the likelihood of rebleeding, and, to a greater extent, by the patients' poor general condition, the presence of a PBDU itself was largely responsible for the high rebleeding rates in PBDUs. CONCLUSION: This is the first study focusing on the nature and treatment outcomes of bleeding PBDUs. PBDUs were associated with much higher rebleeding and mortality rates in comparison to BDUs, and the likelihood of rebleeding may be derived from their unique anatomic location.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Nature and treatment outcomes of bleeding post‐bulbar duodenal ulcers
- Date Crossref
- 26/10/2021
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Akita University Department of Gastroenterology pays non établi dans la noticeUniversité ou école supérieure
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Yamagata University Hospital Division of Endoscopy pays non établi dans la noticeÉtablissement de santé
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Hirosaki University Hospital Division of Endoscopy pays non établi dans la noticeÉtablissement de santé
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Hirosaki University Department of Gastroenterology and Hematology pays non établi dans la noticeUniversité ou école supérieure
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Fukushima Medical University Hospital Department of Endoscopy pays non établi dans la noticeÉtablissement de santé
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Tohoku University Division of Gastroenterology pays non établi dans la noticeUniversité ou école supérieure
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Osaki Citizen Hospital Department of Gastroenterology pays non établi dans la noticeÉtablissement de santé
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Aomori Prefectural Central Hospital Department of Gastroenterology pays non établi dans la noticeÉtablissement de santé
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Ohta Nishinouchi Hospital Department of Gastroenterology pays non établi dans la noticeÉtablissement de santé
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Akita University Hospital pays non établi dans la noticeÉtablissement de santé
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Hiraka General Hospital Department of Gastroenterology pays non établi dans la noticeÉtablissement de santé
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Tohoku Rosai Hospital pays non établi dans la noticeÉtablissement de santé
Department of Gastroenterology — Akita University, Division of Endoscopy — Yamagata University Hospital et Division of Endoscopy — Hirosaki University Hospital, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.