Identification of the phase composition of solid microparticles in the nasal mucosa of patients with chronic hypertrophic rhinitis using Raman microspectroscopy
Rattachement africain : cz, gb. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Abstract Solid particles, predominantly in micron and submicron sizes, have repeatedly been observed as a threat to a human health unique compared to the other textures of the same materials. In this work, the hypothesis the solid metal-based particles play a role in the pathogenesis of chronic hypertrophic rhinitis was investigated in patients who had not responded positively to medication. In the group of 40 randomly selected patients indicated for surgical mucotomy, the presence of solid micro- and submicron particles present in their nasal mucosa was assessed. For comparison, a set of 13 reference samples from patients without diagnosed chronic hypertrophic rhinitis was evaluated. The analysis was performed using Raman microspectroscopy. The advantage of this method is the direct identification of compounds. The main detected compounds in the mucosa samples of patients with chronic hypertrophic rhinitis were TiO2, carbon-based compounds, CaCO3, Ca(Fe, Mg, Mn)(CO3)2 MgCO3, Fe2O3, BaSO4, FeCO3 and compounds of Al and Si, all of which may pose a health risk to a living organism. In the reference samples, only TiO2 and amorphous carbon were found. In the control group mucosa, a significantly lower presence of most of the assessed compounds was found despite the longer time they had to accumulate them due to their higher mean age. Identification and characterisation of such chemicals compounds in a living organism could contribute to the overall picture of the health of the individual and lead to a better understanding of the possible causes not only in the chronic hypertrophic rhinitis, but also in other mucosal and idiopathic diseases.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Identification of the phase composition of solid microparticles in the nasal mucosa of patients with chronic hypertrophic rhinitis using Raman microspectroscopy
- Date Crossref
- 23/09/2021
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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VSB - Technical University of Ostrava Centre for Advanced Innovation Technologies pays non établi dans la noticeUniversité ou école supérieure
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University Hospital Ostrava Institute of Pathology pays non établi dans la noticeÉtablissement de santé
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Northumbria University pays non établi dans la noticeUniversité ou école supérieure
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Medin (Czechia) pays non établi dans la noticeEntreprise
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Faculty of Mining and Geology pays non établi dans la noticeUniversité ou école supérieure
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Faculty of Engineering and Environment Smart Materials and Surfaces Laboratory pays non établi dans la noticeUniversité ou école supérieure
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MEDIN a.s. pays non établi dans la noticeInstitution
Centre for Advanced Innovation Technologies — VSB - Technical University of Ostrava, Institute of Pathology — University Hospital Ostrava et Northumbria University, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.