An analysis to compare the clinical reaction, sensitivity and efficacy of Fusidic acid and mupirocin in S. aureus isolates in pyodermas: A prospective study in tertiary care teaching hospital

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Background: Fusidic acid and mupirocin have been recommended for the treatment of acute staphylococcal skin lesions. Here we will analyze the sensitivity of topical antibiotics like fusidic acid and mupirocin in a series of 205 S. aureus isolates from community acquired pyodermas. Subjects and Methods: Prospective study conducted at the outpatient department of Dermatology, Venereology and Leprosy at Shri Shankaracharya Institute of Medical Sciences Junwani, Bhilai, Distt. Durg, Chhattisgarh,- 490020 between Jan 2019 to Sept 2019. All patients presenting to the outpatient department with primary or secondary pyodermas were eligible for the study. Patients of all age and both sex attending the outpatient department (OPD) of Dermatology with pyoderma after obtaining informed consent to participate in the study. Antibiotic sensitivity for fusidic acid and mupirocin was done for 135 cases and 101 cases respectively. Excluded patients where those who have had a hospital stay in the past one year, those who have already received topical or systemic antibiotics and non- consenting patients. The study was approved by the Institute’s Review Board and Ethics Committee.

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