Quality of Life in Patients With Hypoparathyroidism After Treatment for Thyroid Cancer
Rattachement africain : de, it, pt, pl, jp, in, gb, se, nl, Égypte, cy, at, es, be. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
PURPOSE: Surgical complications such as hypoparathyroidism (HPT) or vocal cord palsy are seldom assessed when the quality of life (QOL) in thyroid cancer patients is investigated. The aim of this study was to measure the QOL difference in thyroid cancer survivors with and without HPT. METHODS: Participants for this analysis were enrolled in 13 countries from a study that pilot-tested a thyroid cancer-specific QOL instrument. They were included if they had been diagnosed with thyroid cancer at least 9 months previously. QOL was measured using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) and some items on HPT symptoms (eg, tingling in fingers or toes). HPT status and other clinical data were extracted from the patients' medical charts. Comparisons of QOL domains between patients with and without HPT were performed using Mann-Whitney U test. The occurrence of HPT-related symptoms was compared using chi-square tests. Multiple ordinal regression analysis was performed to evaluate factors that might affect QOL. RESULTS: Eighty-nine patients participated in this study, 17 of whom were considered to have HPT. Patients in the HPT group reported significantly reduced QOL in 9 of the 15 scales of the EORTC QLQ-C30 compared to patients without HPT. Regression analysis showed that HPT was independently negatively associated with various scales of the QLQ-C30. Both groups showed a high prevalence of typical HPT symptoms. CONCLUSION: Thyroid cancer patients with HPT report significantly impaired QOL compared to thyroid cancer survivors without HPT. The assessment of HPT should be considered when measuring QOL in thyroid cancer patients.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Quality of Life in Patients With Hypoparathyroidism After Treatment for Thyroid Cancer
- Date Crossref
- 11/09/2020
- Éditeur
- The Endocrine Society
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Johannes Gutenberg University Mainz pays non établi dans la noticeUniversité ou école supérieure
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University Medical Center of the Johannes Gutenberg University Mainz pays non établi dans la noticeÉtablissement de santé
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Fondazione IRCCS Istituto Nazionale dei Tumori pays non établi dans la noticeÉtablissement de santé
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Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" pays non établi dans la noticeÉtablissement de santé
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IPO Porto pays non établi dans la noticeÉtablissement de santé
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Jagiellonian University Department of Medical Education pays non établi dans la noticeUniversité ou école supérieure
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Kobe University Hospital Department of Medical Oncology and Hematology pays non établi dans la noticeÉtablissement de santé
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Tirunelveli Medical College pays non établi dans la noticeUniversité ou école supérieure
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Mount Vernon Cancer Centre pays non établi dans la noticeÉtablissement de santé
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Sahlgrenska University Hospital pays non établi dans la noticeÉtablissement de santé
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University of Gothenburg Department of Otorhinolaryngology-Head and Neck Surgery pays non établi dans la noticeUniversité ou école supérieure
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The Netherlands Cancer Institute pays non établi dans la noticeÉtablissement de santé
Johannes Gutenberg University Mainz, University Medical Center of the Johannes Gutenberg University Mainz et Fondazione IRCCS Istituto Nazionale dei Tumori, avec 9 autres affiliations. Pays d’affiliation : Égypte.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.