OTOF-related auditory neuropathy spectrum disorder
Rattachement africain : ru. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
) gene mutations are the most common cause of hereditary ANSD according to investigations in several countries. THE AIM: -related ANSD. PATIENTS AND METHODS: ). RESULTS: mutations, including 6 new variants, were found in 5 children with ANSD (18%). All 5 children had no risk factors for hearing loss and passed hearing screening. OAE and cochlear microphonics were present till the last testing at the age of 4-5 years. ABR were not detectable. The ASSR were measurable bilaterally at all frequencies in all cases, but they did not correlate with behavioral thresholds that revealed severe hearing loss. Hearing thresholds were stable during follow up period. 3 children underwent cochlear implantation. After cochlear implantation auditory nerve action potentials to electric stimulation were detected within normal range. CONCLUSION: testing enables to reveal hearing loss etiology and provide the optimal rehabilitation approach, including cochlear implantation, as early as possible.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- OTOF-related auditory neuropathy spectrum disorder
- Date Crossref
- 01/01/2020
- Éditeur
- Media Sphere Publishing Group
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Les institutions déclarées
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