Seroprevalence of three paramyxoviruses; Hendra virus, Tioman virus, Cedar virus and a rhabdovirus, Australian bat lyssavirus, in a range expanding fruit bat, the Grey-headed flying fox (Pteropus poliocephalus)
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Le résumé fourni par la source
Habitat-mediated global change is driving shifts in species' distributions which can alter the spatial risks associated with emerging zoonotic pathogens. Many emerging infectious pathogens are transmitted by highly mobile species, including bats, which can act as spill-over hosts for pathogenic viruses. Over three years, we investigated the seroepidemiology of paramyxoviruses and Australian bat lyssavirus in a range-expanding fruit bat, the Grey-headed flying fox (Pteropus poliocephalus), in a new camp in Adelaide, South Australia. Over six, biannual, sampling sessions, we quantified median florescent intensity (MFI) antibody levels for four viruses for a total of 297 individual bats using a multiplex Luminex binding assay. Where appropriate, florescence thresholds were determined using finite mixture modelling to classify bats' serological status. Overall, apparent seroprevalence of antibodies directed at Hendra, Cedar and Tioman virus antigens was 43.2%, 26.6% and 95.7%, respectively. We used hurdle models to explore correlates of seropositivity and antibody levels when seropositive. Increased body condition was significantly associated with Hendra seropositivity (Odds ratio = 3.67; p = 0.002) and Hendra virus levels were significantly higher in pregnant females (p = 0.002). While most bats were seropositive for Tioman virus, antibody levels for this virus were significantly higher in adults (p < 0.001). Unexpectedly, all sera were negative for Australian bat lyssavirus. Temporal variation in antibody levels suggests that antibodies to Hendra virus and Tioman virus may wax and wane on a seasonal basis. These findings suggest a common exposure to Hendra virus and other paramyxoviruses in this flying fox camp in South Australia.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Seroprevalence of three paramyxoviruses; Hendra virus, Tioman virus, Cedar virus and a rhabdovirus, Australian bat lyssavirus, in a range expanding fruit bat, the Grey-headed flying fox (Pteropus poliocephalus)
- Date Crossref
- 06/05/2020
- Éditeur
- Public Library of Science (PLoS)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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The University of Adelaide pays non établi dans la noticeUniversité ou école supérieure
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Australian Centre for Disease Preparedness pays non établi dans la noticeStructure de recherche
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CSIRO Health and Biosecurity pays non établi dans la noticeStructure de recherche
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Commonwealth Scientific and Industrial Research Organisation pays non établi dans la noticeOrganisme public
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South Australian Museum pays non établi dans la noticeInstitution
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Zoos Victoria pays non établi dans la noticeInstitution
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School of Animal and Veterinary Sciences pays non établi dans la noticeUniversité ou école supérieure
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Australia Animal Health Laboratory CSIRO Health and Biosecurity Business Unit pays non établi dans la noticeStructure de recherche
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Australian Animal Health Laboratory CSIRO pays non établi dans la noticeStructure de recherche
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South Australia Museum pays non établi dans la noticeInstitution
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Zoos South Australia pays non établi dans la noticeInstitution
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School of Mathematical Sciences pays non établi dans la noticeUniversité ou école supérieure
The University of Adelaide, Australian Centre for Disease Preparedness et CSIRO Health and Biosecurity, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.