Simultaneous EEG-fMRI: A novel approach to localize the Seizure Onset Zone
Rattachement africain : ir. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Affecting daily lives of millions of people, Epilepsy is a common central nervous system (neurological) disorder where cell activity in brain is disturbed, causing recurrent seizures. Epilepsy can be treated commonly by medications. Be that as it may, medications do not always work as well as one may have hoped, and thus, some patients tend to resort to surgeries. The primary challenge in such surgeries, and by extension any other surgery where some part of brain may need to be disabled, disconnected or removed, is managing to pose no threat to the critical healthy textures adjacent or close to the part being operated on. Therefore, the precise localization of epileptic focus is a matter of vital importance in treating this condition. Various algorithms have been proposed to localize the brain sources and thus to determine the epileptic focus, however, none has yet been able to offer a solution to effectively address this issue. With EEG signal containing temporal information and fMRI carrying spatial information, it is hoped that the combination of the two can yield optimal results. In this case study, we first remove the artifacts caused by EEG gradients, and proceed to study the signal in and outside the scanner by localizing the brain sources. The simultaneous processing of EEG-fMRI enables us to make use of the temporal information in EEG to analyze fMRI. Epileptic foci are finally localized based on GLM method. This study has been conducted on 2 medication-resistant patients with epilepsy whose data was recorded in Iran National Brain Mapping Centre. The results suggest a significant improvement in localization accuracy compared to existing methods in the literature. Keywords: Simultaneous EEG-fMRI; Epilepsy; Independent Component Analysis (ICA); Blood-oxygen-level dependent imaging (BOLD); Generalized Linear Model (GLM)
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Simultaneous EEG-fMRI: A novel approach to localize the Seizure Onset Zone
- Date Crossref
- 04/12/2019
- Éditeur
- RAFT IT and Publications Pvt Limited
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Tehran pays non établi dans la noticeUniversité ou école supérieure
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Shahed University pays non établi dans la noticeUniversité ou école supérieure
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Institute for Cognitive Science Studies pays non établi dans la noticeStructure de recherche
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Sharif University of Technology Department of Mechanical and Mechatronics Engineering pays non établi dans la noticeUniversité ou école supérieure
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Tehran University of Medical Sciences pays non établi dans la noticeUniversité ou école supérieure
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Islamic Azad University Department of Biomedical Engineering pays non établi dans la noticeUniversité ou école supérieure
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School of Electrical and Computer Engineering CIPCE pays non établi dans la noticeUniversité ou école supérieure
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Faculty of Engineering Department of Biomedical Engineering pays non établi dans la noticeUniversité ou école supérieure
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Institute for Cognitive Sciences Studies pays non établi dans la noticeStructure de recherche
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School of Medicine Department of Medical Physics and Biomedical Engineering pays non établi dans la noticeUniversité ou école supérieure
University of Tehran, Shahed University et Institute for Cognitive Science Studies, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.