Computational methods for describing the laser-induced mechanical response of tissue

Le résumé fourni par la source

Detailed computational modeling of laser surgery requires treatment of the photoablation of human tissue by high intensity pulses of laser light and the subsequent thermomechanical response of the tissue. Three distinct physical regimes must be considered to accomplish this: (1) the immediate absorption of the laser pulse by the tissue and following tissue ablation, which is dependent upon tissue light absorption characteristics; (2) the near field thermal and mechanical response of the tissue to this laser pulse; and (3) the potential far field (and longer time) mechanical response of witness tissue. Both (2) and (3) are dependent upon accurate constitutive descriptions of the tissue. We briefly review tissue absorption and mechanical behavior, with an emphasis on dynamic loads characteristic of the photoablation process. In this paper our focus centers on the requirements of numerical modeling and the uncertainties of mechanical tissue behavior under photoablation. We also discuss potential contributions that computational simulations can make in the design of surgical protocols which utilize lasers, for example, in assessing the potential for collateral mechanical damage by laser pulses.

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