Frequency and Determinants of Prescribing Antibiotics for Internal Medicine at Donka National Hospital (Guinea)

Résumé fourni par la source

Background: In hospitals, antibiotics are one of the most prescribed drug classes. The purpose of this study was to describe the extent and factors associated with the prescription of antibiotics in the Internal Medicine Department of Donka National Hospital. Material and Methods: A cross-sectional study was conducted from July 30, 2018 to January 31, 2019 among prescribers and patients hospitalized or seen on an outpatient basis. Data were collected by direct interview and through patient records. A multivariate logistic regression was performed to identify the factors associated with antibiotic prescribing. Results: Out of a total of 400 consultants, 82 (21%) patients received antibiotic therapy. Beta-lactam antibiotics were the most prescribed antibiotic (45%) and urogenital infections (24.3%) were the most common indication. In univariate analysis, the consultation by a trainee physician [OR = 3.06 (95% CI: 1.56-6)] was associated with a prescription for antibiotics. Students/students [OR = 1.85 (95% CI: 1.01-3.39)], civil servants [OR = 1.82 (95% CI: 1.02-3.26)], patients residing in Conakry [OR = 2.06 (95% CI: 1.08-3.91)], those hospitalized [OR = 3.16 (95% CI: 1.55-6.46)] and those with a fever [OR = 6.49 (95% CI: 3.84-10.96)] were more likely to receive an antibiotic. Only fever [OR adjusted = 4.30 (95% CI: 2.43-7.61)] remained associated with the prescription of antibiotics in multivariate analysis. Conclusion: The results showed that fever was the factor independently associated with the antibiotic prescription. In a country where malaria is the main cause of fever, the results suggest the need for training health care workers in antibiotic prescribing.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.