Timing of secondhand smoke, pet, dampness or mould exposure and lung function in adolescence
Rattachement africain : nl. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background The relevance of timing of exposure in the associations of secondhand tobacco smoke (SHS), pets, and dampness or mould exposure with lung function is unclear. We investigated the relevance of timing of these exposures for lung function in adolescence. Methods We used data from participants of the Dutch Prevention and Incidence of Asthma and Mite Allergy (PIAMA) cohort with spirometric measurements at ages 12 and 16 years (n=552). Data on residential exposure to SHS, pets, and dampness or mould were obtained by repeated parental questionnaires. We characterised timing of exposure through longitudinal patterns using latent class growth modelling and assessed associations of these patterns with FEV 1 and FVC at ages 12 and 16 and FEV 1 and FVC growth between ages 12 and 16 using linear regression models. Results Childhood SHS exposure was associated with reduced FEV 1 growth/year (95% CI) (−0.34% (−0.64% to −0.04%)). Late childhood and early life pet exposure was associated with increased FEV 1 growth (0.41% (0.14% to 0.67%)) and reduced FVC growth (−0.28% (−0.53% to −0.03%)), respectively, compared with very low exposure. Early life dampness or mould exposure was associated with reduced lung function growth. All time windows of SHS exposure tended to be associated with lower attained lung function and pet exposure tended to be associated with higher FEV 1 . Conclusion SHS exposure during childhood could lead to reduced lung function growth and lower attained lung function in adolescence. While pet exposure in late childhood may not adversely affect lung function, early childhood pet exposure may slow down FVC growth in adolescence.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Timing of secondhand smoke, pet, dampness or mould exposure and lung function in adolescence
- Date Crossref
- 20/11/2019
- Éditeur
- BMJ
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Utrecht University Institute for Risk Assessment Sciences (IRAS) pays non établi dans la noticeUniversité ou école supérieure
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University Medical Center Groningen Department of Pediatric Pulmonology and Pediatric Allergology pays non établi dans la noticeÉtablissement de santé
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University Medical Center Utrecht Julius Center for Health Sciences and Primary Care pays non établi dans la noticeÉtablissement de santé
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National Institute for Public Health and the Environment Prevention and Health Services pays non établi dans la noticeStructure de recherche
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University of Groningen pays non établi dans la noticeUniversité ou école supérieure
Institute for Risk Assessment Sciences (IRAS) — Utrecht University, Department of Pediatric Pulmonology and Pediatric Allergology — University Medical Center Groningen et Julius Center for Health Sciences and Primary Care — University Medical Center Utrecht, avec 2 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.