Baclofen-Induced Dyshidrosiform Bullous Pemphigoid in a Paraplegic Patient Complicated by Methicillin-Resistant Staphylococcus aureus (MRSA) and Urinary Infection.
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Le résumé fourni par la source
Bullous pemphigoid (BP) is an autoimmune disorder which is usually chronic, with blistering that predominantly affects the skin and occasionally the mucosa, and which includes several different types. One of them is a very rare dyshidrosiform type which is localized on the hands and feet with small or large blisters on the palmoplantar surfaces. BP resulting from a drug reaction is a relatively rare occurrence, and so far more than 50 different medications have been identified as triggers. The aim of this article was to present the case of a paraplegic patient who developed this rare dyshidrosiform type of BP while he was being neurologically treated with baclofen. In spite of therapy with systemic and topical corticosteroids and other measures, successful treatment was achieved only after eliminating baclofen from the patient's regimen. His general state of health was seriously endangered due to nasal and skin methicillin-resistant Staphylococcus aureus (MRSA), urinary infection, and oral mycosis (soor), and he was at high risk of sepsis and a fatal outcome. Through our efforts, however, we managed to achieve an excellent outcome. According to our knowledge, this was the first case of baclofen-induced dyshidrosiform BP.
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Sisters of Charity Hospital pays non établi dans la noticeÉtablissement de santé
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Sestre milosrdnice University Hospital Center Department of Dermatovenereology pays non établi dans la noticeUniversité ou école supérieure
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Department of Dermatovenereology University Hospital Center Sestre milosrdnice School of Dental Medicine University of Zagreb pays non établi dans la noticeUniversité ou école supérieure
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Ljudevit Jurak Department of Pathology University Hospital Center Sestre milosrdnice pays non établi dans la noticeUniversité ou école supérieure
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Department of Microbiology and Hospital Infections University Hospital Center Sestre milosrdnice pays non établi dans la noticeUniversité ou école supérieure
Sisters of Charity Hospital, Department of Dermatovenereology — Sestre milosrdnice University Hospital Center et Department of Dermatovenereology University Hospital Center Sestre milosrdnice School of Dental Medicine University of Zagreb, avec 2 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.