Histopathological Characteristic Of Chronic Hbv Infection In Bulgaria

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MedInform 13.9 for F3 and F4 stages, respectively).There was a trend for an increase of the mean age of patients from the subgroups with mild to severe activity grades.The mean age of the patients with LC was significantly higher compared to that of the subgroups of patients with different activity grades, respectively (p= 0.001).There were significant differences between the mean ages of patients with F1, F2 or F3 stages and those of patients with F4 and LC (p=0.015-0.0001).No sex difference was found in the comparison of the mean ages of the patients with the individual grades of activity or stages of fibrosis. ConclusionAbout 30 percent of Bulgarian patients with CHB are cirrhotic before starting antiviral therapy and 10 years older compared to the non-LC CHB patients.Almost three quarters of all patients with CHB were males.Severe histomorphological activity was found in only 1/5 of the patients with CHB and advanced fibrosis in 1/3 of them.There was a trend for an increase of the mean age of patients with CHB from the subgroups with mild to severe activity grade and from F1 to F4 stage, respectively.

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