PHYTOCHEMICAL SCREENING &EVALUATION OF ANTIMICROBIALACTIVITY OF CHONEMORPHA FRAGRANS AGAINST HUMAN PATHOGENIC BACTERIA
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ABSTRACT The present study aimed at evaluating the antimicrobial efficiency of ethanolic leaf extracts of Chonemorpha fragrans, a medicinal plant against four human pathogenic bacteria like Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa using agar well diffusion method and minimum inhibitory concentration and minimum bacterial concentration. Chonemorpha fragrans showed significant activity against all pathogens with its ethanolic extract which showed maximum zone of inhibition and minimum inhibitory concentration against all the experimental strains.The phytochemical analysis carried out revealed the presence ofphytochemicals such as flavonoids, glycosides, alkaloids, gums, mucilage, phytosterols and saponins. The results provide justification for the use of the plant in folk medicine to treat various infectious diseases.Hence the use of plant extract with known antimicrobial properties can be of great significance in therapeutic treatments. KEYWORDS: Antimicrobial activity, Chonemorpha fragrans, Agar well diffusion method, MIC, MBC, Zone of inhibition, Human pathogenic bacteria.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.