De novo Aneurysms

Le résumé fourni par la source

Introduction: Patients who have undergone craniotomy and clipping of an aneurysm are believed to be cured. We report two cases with previous ruptured aneurysms who presented 10 and 14 years later with de novo aneurysms. Methods: The charts of 39 patients who underwent craniotomy and clipping of 52 intracranial aneurysms by a single surgeon at a single institution from July 1999 to June 2003 were reviewed. Medline search for published English literature on de novo aneurysms was conducted from 1964 to 2003. Results: Two female patients out of 39 (5%) were found to have de novo aneurysms in our series. Mean age was 47. One patient presented again with SAH. Both were found to have multiple aneurysms less than 6 mm in size. There are 77 cases of de novo aneurysms in the English literature. Sixty-two (81%) patients presented with ruptured de novo aneurysm. The mean age of initial aneurysm presentation was 42.2 years, with average time interval between this and diagnosis of de novo aneurysm formation was 9.2 years. The female to male ratio is 2:1. Multiple aneurysms were found in 17 (22%) and 16 (21%) patients in the initial presentation and the de novo presentation respectively. Conclusions: Patients who undergo craniotomy and aneurysm clipping at an early age may benefit from follow up imaging studies for up to 20 years. Helicoidal CT angiogram with 3D reconstruction will allow for non-invasive follow up.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.