Laparoscopic lymph nodes dissection for advanced gastric cancer: the current status and the perspective

Le résumé fourni par la source

The laparoscopic gastrectomy (LG) with D2 lymph node dissection (LND) for advanced gastric cancer (AGC) have been widely done.However, the applicability to more advanced disease is still under debate.Actually, there are a lot of technical demands against D2 LND for AGC, e.g., total omentectomy, splenic hilar node dissection, and the management for bulky lymph nodes, etc.Recently, extensive research has been gradually performed in the field of LG for AGC and demonstrated that LG for AGC is a safe and feasible procedure with better short-term outcomes compared with open gastrectomy.Also, large-scaled phase III trials are ongoing, and their long-term outcomes are awaited the publication in the near future.LG with D2 LND by expert surgeons under the cautious indications could be acceptable treatment for locally AGC.On the other hand, we should keep searching for solutions to the technical or oncological issues, and long-term outcome of phase III study should be warranted for standard treatment.Robotic surgery, LG following neoadjuvant chemotherapy, or conversion therapy using LG for several stage IV patients may help us clear the technical hurdles, and may show survival advantages in the future.

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