The 10-year functional outcome of schizophrenia in Butajira, Ethiopia
Rattachement africain : Éthiopie, gb, ca. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Long-term functional schizophrenia outcomes are not well characterized in low-income environments because of the rarity of prospective studies. OBJECTIVES: To assess and describe long-term schizophrenia's functional outcomes and potential outcome predictors. METHODS: Following a baseline assessment, 316 people with schizophrenia were studied for 10 years, on average. Of the total, 79 were incident cases: cases with onset of the illness occurring two years or less from entry into the study. SF-36 scores of physical and social functioning were used to assess functional outcomes. Linear mixed models were employed to evaluate the association of functioning with potential predictors. RESULTS: Social and physical functioning scores regarding the cohort were lower than the population's norm for most of the follow-up period. Incident cases had better function than prevalent cases. Fifteen percent of incident and 30% of prevalent cases had reduced social functioning for at least six years. Declining symptom severity during the follow-up period was significantly associated with improvement in social functioning. When baseline functioning was controlled for, the long-term trend in functionality was not associated with demographic or illness characteristics (age and speed of onset, duration of illness and neuroleptic use at entry, substance use, and medication adherence). CONCLUSION: Long-term physical and social functioning of the population with schizophrenia were significantly lower than the population norm. A significant proportion of the cohort had lower functioning for the long-term. Functioning was not associated with demographic or illness characteristics of the study population.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- The 10-year functional outcome of schizophrenia in Butajira, Ethiopia
- Date Crossref
- 01/03/2019
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Addis Ababa University Aklilu Lemma Institute of Pathobiology Addis Ababa University, Éthiopie (code pays fourni par la source)Université ou école supérieure
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Brighton and Sussex Medical School pays non établi dans la noticeUniversité ou école supérieure
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Horizon Health Network pays non établi dans la noticeÉtablissement de santé
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King's College London Institute of Psychiatry pays non établi dans la noticeUniversité ou école supérieure
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School of Public Health Department of Preventive Medicine Addis Ababa University, Éthiopie (pays nommé en fin d’affiliation)Université ou école supérieure
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College of Health Sciences Centre for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa) Addis Ababa University, Éthiopie (pays nommé en fin d’affiliation)Université ou école supérieure
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Department of Global Health & Infection pays non établi dans la noticeInstitution
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School of Medicine Department of Psychiatry Addis Ababa University, Éthiopie (pays nommé en fin d’affiliation)Université ou école supérieure
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Department of Psychiatry pays non établi dans la noticeInstitution
Aklilu Lemma Institute of Pathobiology — Addis Ababa University (Addis Ababa University, Éthiopie), Brighton and Sussex Medical School et Horizon Health Network, avec 6 autres affiliations. Pays d’affiliation : Éthiopie.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.