Accès ouvert déclaré
2019
article
National prospective cohort study of the burden of acute small bowel obstruction
Matthew J. Lee, Adele Sayers, Thomas M Drake, Philip J. Marriott, I D Anderson, Simon P. Bach, Mike Bradburn, Daniel Hind, Azmina Verjee, Nicola Fearnhead, John Abercrombie, Austin G. Acheson, Derek Alderson, Michael Davies, Zaed Hamady, Marianne Hollyman, Sarah Hare, John Northover, Christopher Alan Lewis, Malcolm McFall, Aravinth Murugananthan, David Murray, Pritam Singh, Gillian Tierney, Ciaran Walsh, Jonathan Wild, Timothy Wilson, S. Abbott, Yasser Abdulaal, Salim Afshar, F Akram, Elaine M Aldred, Adaugo Amajuoyi, Daren Anderson, O. D. Anderson, Alexander Andreou, A Ansari, Rohan Ardley, Fatima Arshad, O Ashour, A Athem, M Athersmith, Fares Ayoub, Bilal Azhar, T Badenoch, Colin Baillie, Joseph Barker, Sarah Barker, Benjamin Barkham, Ralf Baron, Jenifer Barrie, Nick Battersby, G Bazoua, Nebil Behar, Shashi Bellam, C. Berger, Samrat Singh Bhandarı, S Bhasin, Sarah N. Biggs, Carly Bisset, Lucy Blake, Alex Boddy, P Bohra, Michael R. Boland, Håkon A. Bolkan, George Bouras, Graham Branagan, H Brewer, C Briggs, James Brown, Oliver Brown, K Burns, K Butcher, Ben Byrne, Leah Campbell, Cameron P. Capper, Mark Cartmell, Therese V. Cash, Sheila L. Chan, N Chandratreya, Jennifer Chapman, Stephen J. Chapman, Alexandros Charalabopoulos, C Cheek, Ksh Chok, Keith Wai Keong Choong, P Coe, Philip G. Conaghan, G. Conn, Nicole Cook, Sheldon C. Cooper, Julie Cornish, Christopher Michael Jason Cox, Peter Coyne, Richard Crook, Jack Crozier, Giulio Cuffolo, K Da Costa, L Silva, Bhupati Bhusan Das, Mark Davenport, Justine Davies, Thomas Davies, A Day, S Dean, Georgia Demetriou, Fungai Dengu, Richard Dennis, P Dent, Mohammed Deputy, Laurence Devoto, Giuseppe Di Benedetto, Shiva Dindyal, Eric D. Donnelly, Paul Doody, Eleftheria Douka, H Dowson, H Edent, Keith Edgerton, N Ekpete, O Elamin, M Eljaafari, Nora Y. Elsaid, Jennifer Evans, Martin D.D. Evans, Renee Ewe, Anne Ewing, Klaire Exarchou, Rosalind Fallaize, Morad Faoury, S. Farag, G Faulkner, Owain Fisher, Jordan Fletcher, Amir Forouzanfar, Ashley A. Foster, Ray Fox, Nader Francis, V Fretwell, Didier Fung, Emanuele Gammeri, J Garnham, Alexandra Gilbert, C Gill, Allan M. Golder, Tine Grégoir, T Grove, Siona Growcott, H Habib, J. B. Haddow, Constantine Halkias, Laura Hancock, Tarek N. Hanna, Athur Harikrishnan, Grant Harris, James Harvey, Jemma Hawkins, Rachel Heard, R Heartshorne, S Heller, L Hendra, N Heywood, B. M. Hobson, Carla Hope, P Hopley, Tanvir Hossain, T Hubbard, Alexandra Humphreys, H Ikram, M Ioannis, Muhammad Javed Iqbal, Nayyer Iqbal, Ritu Jain, P Jenkinson, A. Jones, Carolyn Jones, Louise Jones, K Joshi, P Jull, G Kakaniaris, R Kallam, P Kang, Samina Kauser, Farasat Kazmi, Martha S. Kedrzycki, Sarah Kelly, Misbah Khan, T Khan, Gentry Teng King, A Kisiel, Christos Kitsis, IK Kolawole, S Korambayil, S Kosasih, Angeliki Kosti, Ahmed Kotb, S. Kouris, K Kshatriya, Gloria Inés Lafaurie, R Lal, A Lau, T Lazim, Antonio Lazzaro, K Lee, Rebecca Lefroy, D Leinhardt, Hannah Lennon, Bruce D. Levy, Eric Lim, S. Lindley, P Lloyd, Dafydd Locker, Sonia Lockwood, Christopher F. Lowe, Jonathan N. Lund, Raimundas Lunevičius, Aidan Lunt, S Lutfi, S Luwemba, P Mahankali‐Rao, S. Mahroof, S Majid, A Malik, K. Malik, K. Mann, S Mansour, Rahee Mapara, Claude Martin, R. H. Martin, L Massey, J. Mathias, Pawan Mathur, Karen Maude, D. Ray McArthur, Simon McCluney, Siobhan McKay, Angus McNair, Derek McWhirter, Katie Mellor, S Mir, Anurag Mishra, P Mistry, V Miu, M Moat, E. Mohamed, I. Mohamed, M Mondragon‐Pritchard, N. Moore, H Morris, Victoria Morrison-Jones, J Moss, Susan Moug, D Mountford, Kadum Muhammad, John Mulholland, Michelle Mullan, Ellen Murgitroyd, Kavipriya Murugaiyan, Abigail Kate Myers, Ioannis Mykoniatis, T. Nash, Anwar H. Nassar, Chin K. Ng, Pamela Ng, Khang Nguyen, F. G. Nicholas, Jennifer Nowers, Clare Nugent, Nicole Obeid, John M. O’Callaghan, R O'Hara, Oluchi Oke, James Olivier, A O’Neill, Stephen O’Neill, Daniel Osei‐Bordom, L. Osgood, Spyros Panagiotopoulos, B Panchasara, Pooja Patel, R Patel, Krystian Pawelec, Cathy Payne, Kristina K. Pearson, Giordano Perin, I Peristerakis, L Phelan, J Phillips, J Pitt, K Plunkett‐Reed, A Pouzi, M Pouzi, Anathea C. Powell, Sarah Pywell, Nabeel Qureshi, MM Rahman, S Ramcharan, Madeeha Rashid, Abdul Rehman, S Rehman, C Rengifo, E. Richards, D. Robinson, Bárbara Rossi, F Rutherford, Iannish Sadien, Tahir Saghir, G Salahia, Bart L. Scott, Kelly Scott, Andrew Seager, Stella Seal, E Sezen, Fadlo Shaban, P Shah, A Sharpe, Veeranna Shatkar, Andrea Sheel, T Shields, Arifa Siddika, R Simson, Siddhartha Singh, Paul Skaife, Michael E. Kelly, Asheley Cockrell Skinner, N. Slim, Neil Smart, Fiona Smith, Daron Smith, Arsha Sreedhar, L Stevenson, Martyn Stott, N Stylianides, Sriram Subramonia, M Swinkin, M Swinscoe, Warda Tahir, Katalin Takács, Kelvin Bryan Tan, S Tani, Nichole T. Tanner, Dan Tao, Maxwell D. Taylor, B Thava, K Thippeswamy, Christophe Thomas, C Thompson‐Reil, C Thorn, F. Tongo, Gábor Tóth, Jennifer Turnbull, C. Valero, Gijs van Boxel, M Varcada, Nicholas T. Ventham, Dale Vimalachandran, Wade Tp, Arsalan Wafi, Morgan Walker, N Walker, T.G. Walker, Una Walsh, R Warner, Nora L. Watson, J W H Watt, C Weegenaar, Malcolm West, Lauren N. Whitehurst, M Whyler, Sanjaya Wijeyekoon, G. Williams, Andrew Williamson, Anke Winter, Lewis Wolpert, Jackie Wong, Evie Yeap, T Yeong, S Zaman, B Zappa, Dimitrios Zosimas, Fatima Arshad, Nabeel Qureshi, Shahzaib Rehan, J Williamson
65Citations signalées — pas une note de qualité
14Institutions déclarées
1Pays d’affiliation déclarés
Résumé fourni par la source
Background: Small bowel obstruction is a common surgical emergency, and is associated with high levels of morbidity and mortality across the world.The literature provides little information on the conservatively managed group.The aim of this study was to describe the burden of small bowel obstruction in the UK.Methods: This prospective cohort study was conducted in 131 acute hospitals in the UK between January and April 2017, delivered by trainee research collaboratives.Adult patients with a diagnosis of mechanical small bowel obstruction were included.The primary outcome was in-hospital mortality.Secondary outcomes included complications, unplanned intensive care admission and readmission within 30 days of discharge.Practice measures, including use of radiological investigations, water soluble contrast, operative and nutritional interventions, were collected.Results: Of 2341 patients identified, 693 (29⋅6 per cent) underwent immediate surgery (within 24 h of admission), 500 (21⋅4 per cent) had delayed surgery after initial conservative management, and 1148 (49⋅0 per cent) were managed non-operatively.The mortality rate was 6⋅6 per cent (6⋅4 per cent for non-operative management, 6⋅8 per cent for immediate surgery, 6⋅8 per cent for delayed surgery; P = 0⋅911).The major complication rate was 14⋅4 per cent overall, affecting 19⋅0 per cent in the immediate surgery, 23⋅6 per cent in the delayed surgery and 7⋅7 per cent in the non-operative management groups (P < 0⋅001).Cox regression found hernia or malignant aetiology and malnutrition to be associated with higher rates of death.Malignant aetiology, operative intervention, acute kidney injury and malnutrition were associated with increased risk of major complication.Conclusion: Small bowel obstruction represents a significant healthcare burden.Patient-level factors such as timing of surgery, acute kidney injury and nutritional status are factors that might be modified to improve outcomes.* Members of the NASBO steering group and NASBO collaborators are co-authors of this study and are listed in Appendices S1 and S2 (supporting information)
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- National prospective cohort study of the burden of acute small bowel obstruction
- Date Crossref
- 22/02/2019
- Éditeur
- Oxford University Press (OUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude et ne compte pas comme une seconde source scientifique indépendante.
Institutions déclarées
Une affiliation ne permet pas de déduire la nationalité d’un auteur.
Sujets associés
Intestinal and Peritoneal AdhesionsAppendicitis Diagnosis and ManagementBiliary and Gastrointestinal Fistulas