The impact of arterial hypertension on left ventricular strain in patients with aortic stenosis and preserved ejection fraction
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Le résumé fourni par la source
OBJECTIVE: The influence of arterial hypertension on aortic stenosis severity is still controversial. The aim of this study was to evaluate the influence of hypertension on LV strain in patients with moderate and severe aortic stenosis. METHODS: This cross-sectional study included 115 patients with moderate and severe aortic stenosis and preserved LV ejection fraction (>50%) and 89 age-matched normotensive and hypertensive controls who underwent comprehensive echocardiographic examination. Aortic stenosis patients were divided into normotensive and hypertensive groups. RESULTS: There was no significant difference in LV ejection fraction between hypertensive and normotensive aortic stenosis patients. LV mass index gradually increased with the grade of aortic stenosis. LV global longitudinal strain, as well as endocardial and epicardial longitudinal strains, was significantly lower in hypertensive patients with severe aortic stenosis than in their normotensive counterparts. There was no significant difference in LV global circumferential strain between normotensive and hypertensive patients with severe aortic stenosis. Among patients with moderate aortic stenosis, there was no difference in global longitudinal strain between normotensives and hypertensive patients, whereas circumferential was significantly lower in hypertensive patients. LV radial strain was reduced in patients with severe aortic stenosis than in control subjects. SBP and mean aortic valve gradient were associated with LV global longitudinal and circumferential strains in aortic stenosis patients independently of LV mass index, LVEF, age and BMI. CONCLUSION: Hypertension had additional significant negative influence on LV mechanics in patients with significant aortic stenosis. Blood pressure was associated with LV global longitudinal and circumferential strains in aortic stenosis patients independently of main clinical and demographic characteristics.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- The impact of arterial hypertension on left ventricular strain in patients with aortic stenosis and preserved ejection fraction
- Date Crossref
- 01/04/2019
- Éditeur
- Ovid Technologies (Wolters Kluwer Health)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University Hospital Center Dr Dragiša Mišović pays non établi dans la noticeÉtablissement de santé
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University of Milan pays non établi dans la noticeUniversité ou école supérieure
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IRCCS Istituto Auxologico Italiano pays non établi dans la noticeÉtablissement de santé
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University of Milano-Bicocca pays non établi dans la noticeUniversité ou école supérieure
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University Clinical Hospital Center 'Dr Dragisa Misovic - Dedinje Department of Cardiology pays non établi dans la noticeUniversité ou école supérieure
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fax: +381 112411464 pays non établi dans la noticeInstitution
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Clinical Centre of Serbia pays non établi dans la noticeÉtablissement de santé
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University Milano-Bicocca Clinica Medica pays non établi dans la noticeUniversité ou école supérieure
University Hospital Center Dr Dragiša Mišović, University of Milan et IRCCS Istituto Auxologico Italiano, avec 6 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.