Hypokalemic Periodic Paralysis: Reports of Two Cases and Brief Review
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Le résumé fourni par la source
Hypokalemic periodic paralysis (HPP) is a rare autosomal dominant channelopathy characterized by skeletal muscle weakness or paralysis when there is a fall in potassium levels in blood. Weakness may be mild and limited to certain muscle groups or more severe causing generalized paralysis. During an attack, reflexes may be diminished or absent. Attacks may last for a few hours or persist for several days, ultimately resulting in complete recovery. Some patients may develop chronic muscle weakness later in life. Recurrent muscle weakness accompanied by hypokalemia and exclusion of other causes help establish the diagnosis. Potassium supplementation is the mainstay of treatment of acute illness. Lifestyle modification with or without pharmacotherapy in the form of carbonic anhydrase inhibitors and/ or spironolactone can prevent future attacks. Here, we present two cases of HPP, the first one had no positive family history and responded to oral potassium and spironolactone, while the second case had family history suggestive of HPP and was managed with potassium and eplerenone. Birdem Med J 2019; 9(1): 74-79
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Hypokalemic Periodic Paralysis: Reports of Two Cases and Brief Review
- Date Crossref
- 12/01/2019
- Éditeur
- Bangladesh Journals Online (JOL)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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National Institute of Cardiovascular Diseases Department of Cardiology pays non établi dans la noticeOrganisme public
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Bangladesh Institute of Research and Rehabilitation for Diabetes Endocrine and Metabolic Disorders pays non établi dans la noticeÉtablissement de santé
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Bangladesh Institute of Research and Rehabilitation in Diabetes Department of Nephrology pays non établi dans la noticeStructure de recherche
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National Institute of Kidney Diseases & Urology (NIKDU) Department of Nephrology pays non établi dans la noticeStructure de recherche
Department of Cardiology — National Institute of Cardiovascular Diseases, Bangladesh Institute of Research and Rehabilitation for Diabetes Endocrine and Metabolic Disorders et Department of Nephrology — Bangladesh Institute of Research and Rehabilitation in Diabetes, avec 1 autre affiliation.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.