P5619Correlation between dobutamine stress echocardiography and invasive fractional flow reserve in patients with known moderate coronary artery stenosis

Résumé fourni par la source

Background: Dobutamine stress echocardiography (DSE) and invasive fractional flow reserve (FFR) are frequently used and accepted methods in evaluation of myocardial ischemia. There are strong evidences about the prognostic value of DSE in cardiovascular events, such as death or myocardial infarction, but similar data about FFR are equivocal. Purpose: In our prospective trial, we sought to compare the DSE and FFR in patients with moderate coronary artery disease (mCAD). Methods: From December 2014 to December 2016, patients were enrolled with mCAD (30–70% diameter stenosis). Enrolment was indicated by the interventional cardiologist, if mCAD was shown on the coronary angiography by visual assessment. All DSE and FFR measurements were performed within 3 months. FFR <0.8 or new wall motion abnormality in ≥2 contiguous myocardial segments on DSE was considered as abnormal. The following DSE parameters were determined: number of affected myocardial segments (AMS), affected segments' wall motion score (AMS-WMS), wall motion score index (WMSI) at rest and at peak dose of dobutamine, rest/peak WMSI ratio and delta WMSI (rest-peak). Patients with left main coronary stenosis were excluded. In comparison, DSE was used as standard method.

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