P6381The left atrial appendage morphology correlates with stroke risk in patients with sinus rhythm

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Objectives: Ischemic strokes without a well-defined etiology are labeled as cryptogenic, and account for 30–40% of strokes in the registries. The left atrial appendage (LAA) is the most typical origin for intracardiac thrombus formation when associated with atrial fibrillation. We examined whether LAA morphology detected with transesophageal echocardiography (TEE) constitutes a risk factor of thrombus formation and cryptogenic stroke in patients without atrial fibrillation. Aim: To correlate LAA morphology detected by TEE with the incidence of stroke/transient ischemic attack (TIA) in patients without atrial fibrillation. Methods: 150 consecutive pts (90 F, 60 M) with a mean age of 30.9±19.2 (16–59) years with the history of cryptogenic cerebrovascular event (TIA/stroke) and normal sinus rhythm, who underwent TEEs, were analyzed. The patients with PFO were excluded. The diagnosis of stroke was based on the occurrence of a new and abrupt focal neurological deficit, with neurological signs and symptoms persisting for >24 hours, subsequently confirmed by computed tomography and/or MRI.

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