A Study on the Immune Status of Children with Wheezing and Parasitic Infection

Le résumé fourni par la source

The aim of this study was to identify the parasitic infection and the associated allergic condition by studying the stool samples of the wheezing children and to correlate, the total serum IgE antibody levels in those children. Further to study the type of parasites commonly involved in these rural area. A total of 76 stool and blood samples were collected from the wheezing children attended the allergy clinic at the Pediatric out patent department of Karpaga Vinayaga Institute of Medical Science and Research Centre, during a period of six months. Stool samples of children were examined microscopically for the presence of ova/ cysts/ whole parasite and the body segments using saline and iodine wet mount preparations. Serum samples were tested for total IgE antibodies by Turbidimetric immunoassay. Results were analyzed, among the 76 stool samples examined from the wheezing children, 48 are found to be positive contributing to a prevalence of 63.2 % of intestinal parasitic infection in the study population. The most common intestinal parasite was found to be Entamoeba histolytica (33.3%) followed by hook worm (27.1 %) and Giardia intestinalis (23 %). Other less commonly detected parasites were cyst of E. coli in 5 cases (10.4%), ova of Ascaris lumbricoides (6.2%). A high prevalence of intestinal parasites was observed in the wheezing children. Further the children with parasite infection showed a higher level of total IgE in their serum.

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