Association between perceived level of stress, clinical characteristics and psychopathological symptoms in women with systemic lupus erythematosus.
Rattachement africain : es. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
OBJECTIVES: To evaluate psychopathological status and stress level from a sample with SLE; compare mental functioning and stress levels between women with SLE and healthy women; determine whether disease duration, disease activity, cumulative organ damage and stress have an influence on psychopathological symptoms in SLE patients; and evaluate whether perception of stress is related to SLE severity. METHODS: We conducted a cross-sectional study of 425 participants; 202 women with SLE, with an average age (SD) of 36.61 (10.15), and 223 healthy women, with age-matched controls. The assessment included the clinical characteristics (disease duration, SLE activity, cumulative organ damage, pharmacotherapy), the Symptom Checklist-90-Revised (SCL-90-R) and the Perceived Stress Scale. Descriptive, comparative, univariate and multivariate analysis were performed. RESULTS: SLE patients showed psychopathological alterations in the somatisation, obsessive-compulsive and positive discomfort subscales of SCL-90-R. Women with SLE reported significantly higher scores on the psychopathological dimensions and perceived stress compared to healthy women, except for paranoid ideation. Disease duration, SLE activity, cumulative organ damage, and perceived stress were shown to be significant predictors of psychopathological manifestations, explaining a range, between 20 and 43%, of variance across SCL-90-R dimensions. Moreover, perceived stress was related to SLE activity, after controlling for psychopathological dimensions. CONCLUSIONS: The psychopathological manifestations in SLE appeared to be influenced by perceived stress, disease duration, disease activity and cumulative organ damage. In turn, perceived stress was associated with disease severity. This knowledge may contribute to a more comprehensive perspective of these manifestations in the SLE population in the clinical setting.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
Où se fait cette recherche
-
Universidad de Granada pays non établi dans la noticeUniversité ou école supérieure
-
Centro de Investigación Mente pays non établi dans la noticeStructure de recherche
-
University of Alicante pays non établi dans la noticeUniversité ou école supérieure
-
Complejo Hospitalario Universitario de Granada pays non établi dans la noticeÉtablissement de santé
-
Hospital Universitario San Rafael pays non établi dans la noticeÉtablissement de santé
-
University of Granada Department of Clinical Psychology pays non établi dans la noticeUniversité ou école supérieure
-
Faculty of Health Sciences Department of Physiotherapy pays non établi dans la noticeUniversité ou école supérieure
-
Hospital Campus de la Salud pays non établi dans la noticeÉtablissement de santé
-
University Hospitals Department of Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
-
San Rafael University Hospital pays non établi dans la noticeUniversité ou école supérieure
Universidad de Granada, Centro de Investigación Mente et University of Alicante, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.