Protein Interactions and Nanomaterials: A Key Role of the Protein Corona in Nanobiocompatibility

Le résumé fourni par la source

The protein corona is still somewhat of a mysterious consequence of the nanoparticles’ application in theranostics. In this review, several critical aspects related to the protein corona are described, in particular which influences more specifically its formation, how to evaluate/characterize it, and what interactions to expect when the nanoparticle and the protein corona are inside the cell. Despite these issues, which have been studied in a general way, it has been verified that there’s still much information missing when it comes to specific nanoparticles. Here, a few proteins are also highlighted as examples, which have been identified as part of the protein corona; in addition, several factors related to the formation of protein corona are discussed due to their important role in the different adsorbed proteins.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.