142 Efficacy and Safety of Traditional Chinese Medicine Qiaoshao Formula Combined with Dapoxetine in the Treatment of Premature Ejaculation in Chinese Men: a Real-world Study

Le résumé fourni par la source

To make a real-world study on the efficacy and safety of Qiaoshao Formula (QSF) combined with Dapoxetine for the treatment of premature ejaculation (PE). A total of 245 patients ,aged 20-50 years, duration of ≥ 6 months, stability partner, sex life frequency ≥ 4 times / month, diagnostic criteria with the 2014 guide of ISSM for PE, were collected from April to July 2017 in multiple observation centers. According to patient's own choice, not random, the patients were divided into combination of Chinese and Western medicine group( n = 155,CWMG): QSF(consisted of Fructus Forsythiae 20 g, Radix Paeoniae Alba 15 g, Radix Bupleuri 15 g, Morinda offcinalis How 15 g, Rhizoma Dioscoreae 15 g, and so on, twice a day) combined with dapoxetine (Priligy,Menarini Co., Ltd) , and Western medicine group (dapoxetine, n =90,WMG) . There were no significant differences between the two groups in age, course of disease, premature ejaculation profile (PEP) and TCM syndrome scores (P> 0.05). But the intra-vaginal ejaculation latency time (IELT) in two groups was significant difference (P<0.05), WMG was longer. After treatment for 4 weeks and 8 weeks, the subjects were interviewed, and the IELT , PEP , clinical global impression change (CGIC) and adverse reactions (AEs) were recorded respectively; Then the drug was stopped and followed up again 4 weeks later.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.