MP44-08 PATTERNS OF PRESCRIBING AND MONITORING TESTOSTERONE REPLACEMENT THERAPY AMONG 40,081 USERS IN BRITISH COLUMBIA BETWEEN 1997-2013

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effectiveness, cost, or cosmesis.Our objective was to define parental preferences for VUR treatments using a novel technique, multiprofile case best-worst scaling (BWS).METHODS: Preference data from a community sample of US parents were collected via survey instrument with multimedia VUR introduction published on Amazon's Mechanical Turk online work interface.The survey used multiprofile case BWS to evaluate part-worth utilities of VUR treatment attributes.Attributes and their levels were chosen based on extensive review of the VUR literature (Table ).The BWS choice-based conjoint design was constructed and data were analyzed with best minus worst proportions (frequency an attribute is chosen best minus frequency chosen worst, B-W) and multinomial logistic regression (MNL) all using Sawtooth Software Lighthouse Studio 9.5.2.RESULTS: 228 parents completed the instrument.Each attribute was significant in the MNL model (all p<0.001).B-W and partworth utilities for effectiveness, societal cost, all complication rate, and length of hospital stay showed within-attribute trends consistent with theory (Table ).The part-worth utility of cosmesis/invasiveness of endoscopic treatment was significantly larger than those of both surgeries (both p¼0.02).Effectiveness had the highest average importance (50.7%); complication rate (20.9%), doctor recommendation (12.7%), cosmesis/invasiveness (6.2%), length of stay (6.0%), and societal cost (3.5%)were less important.Constructed treatments of attribute level part-worth utility bundles corresponding to current VUR treatments suggested a parent from our sample would select open surgery 74.9% of the time, compared to MIS, endoscopic treatment, and antibiotic prophylaxis 9.6%, 8.9%, and 6.6% of the time, respectively.CONCLUSIONS: Treatment effectiveness and complication rate were the most important attributes ranked by parents in this survey.Tailoring discussion toward distinct treatment outcomes, therefore, may improve the shared decision-making process.

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