Cardiorespiratory fitness and age‐related arterial stiffness in women with systemic lupus erythematosus
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Le résumé fourni par la source
BACKGROUND: The aim of this study was twofold: (i) to examine the association of cardiorespiratory fitness with arterial stiffness in women with systemic lupus erythematosus; (ii) to assess the potential interaction of cardiorespiratory fitness with age on arterial stiffness in this population. MATERIALS AND METHODS: A total of 49 women with systemic lupus erythematosus (mean age 41.3 [standard deviation 13.8] years) and clinical stability during the previous 6 months were included in the study. Arterial stiffness was assessed through pulse wave velocity (Mobil-O-Graph® 24 hours pulse wave velocity monitor). Cardiorespiratory fitness was estimated with the Siconolfi step test and the 6-minute walk test. RESULTS: Cardiorespiratory fitness was inversely associated with pulse wave velocity in crude analyses (P < .05), although this relationship was attenuated when age and other cardiovascular risk factors were controlled. There was a cardiorespiratory fitness × age interaction effect on pulse wave velocity, regardless of the test used to estimate cardiorespiratory fitness (P < .001 for the Siconolfi step test; P = .005 for the 6-minute walk test), indicating that higher cardiorespiratory fitness was associated with a lower increase in pulse wave velocity per each year increase in age. CONCLUSIONS: The results of this study suggest that cardiorespiratory fitness might attenuate the age-related arterial stiffening in women with systemic lupus erythematosus and might thus contribute to the primary prevention of cardiovascular disease in this population. As the cross-sectional design precludes establishing causal relationships, future clinical trials should confirm or contrast these findings.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Cardiorespiratory fitness and age‐related arterial stiffness in women with systemic lupus erythematosus
- Date Crossref
- 02/02/2018
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Hospital Universitario Virgen de las Nieves pays non établi dans la noticeÉtablissement de santé
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University of Almería pays non établi dans la noticeUniversité ou école supérieure
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Universidad de Granada pays non établi dans la noticeUniversité ou école supérieure
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Systemic Autoimmune Diseases Unit Department of Internal Medicine “Virgen de las Nieves” University Hospital Granada Spain pays non établi dans la noticeUniversité ou école supérieure
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"Virgen de las Nieves" University Hospital Department of Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
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Department of Physical Education and Sport Faculty of Sport Sciences University of Granada Granada Spain Department of Physical Education and Sport pays non établi dans la noticeUniversité ou école supérieure
Hospital Universitario Virgen de las Nieves, University of Almería et Universidad de Granada, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.