To compare the efficacy of topical negative pressure dressing with that of conventional moist wound dressings, in healing of wounds

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Background: Wounds and their management are fundamental to the practice of surgery. In the past 15 years there have been significant advances in complex acute and chronic wound management. One of the most significant discoveries was the improvement in wounds with negative pressure–assisted wound closure. The aim and objective of the study was efficacy of topical negative pressure dressing with that of a control group using conventional moist wound dressings, in healing of wounds, were assessed with quality of wound healing.Methods: This prospective randomized controlled study 50 patients with acute and traumatic wounds, sub-acute wounds, chronic open wounds, of which 25 patients underwent topical negative pressure dressing. The remaining 25 patients underwent conventional moist wound dressings. The results were compared after second week. Wounds were assessed depending on wound size and percentage of reduction of wound size, wound bed score and increase in wound bed score, percentage of granulation tissue cover, graft take up as the percentage of ulcer surface area.Results: Our present study shows significant reduction in wound size, in the study group 19.52 cm2 as compare to control group, (6.64 cm2) found to be statistically significant (p <0.001). There is significant increase in wound bed score in the study group (mean difference was 9.60±2.16) where as in the control group there was not much increase in wound bed score (mean difference was 5.12±1.99) (p-valve 0.00001) which is statistically significant. The % of granulation tissue formation in the study group was 81.0±8.29 and in the control group was 53.60±19.23.Conclusions: Topical negative pressure dressing was better than conventional wound dressings in quality of wound healing.

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