Factors to improve the interobserver agreement for gastric atrophy and intestinal metaplasia: consensus of definition and criteria
Rattachement africain : kr. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
AIMS: Intestinal metaplasia and atrophy of the gastric mucosa are associated with Helicobacter pylori infection and are considered premalignant lesions. The updated Sydney system is used for these parameters, but experienced pathologists and consensus processes are required for interobserver agreement. We sought to determine the influence of the consensus process on the assessment of intestinal metaplasia and atrophy. METHODS AND RESULTS: Two study sets were used: consensus and validation. The consensus set was circulated and five gastrointestinal pathologists evaluated them independently using the updated Sydney system. The consensus of the definitions was then determined at the first consensus meeting. The same set was recirculated to determine the effect of the consensus. The second consensus meeting was held to standardise the grading criteria and the validation set was circulated to determine the influence. Two additional circulations were performed to assess the maintainance of consensus and intraobserver variability. Interobserver agreement of intestinal metaplasia and atrophy was improved through the consensus process (intestinal metaplasia: baseline κ = 0.52 versus final κ = 0.68, P = 0.006; atrophy: baseline κ = 0.19 versus final κ = 0.43, P < 0.001). Higher interobserver agreement in atrophy was observed after consensus regarding the definition (pre-consensus: κ = 0.19 versus post-consensus: κ = 0.34, P = 0.001). There was improved interobserver agreement in intestinal metaplasia after standardisation of the grading criteria (pre-standardisation: κ = 0.56 versus post-standardisation: κ = 0.71, P = 0.010). CONCLUSIONS: This study suggests that interobserver variability regarding intestinal metaplasia and atrophy may result from lack of a precise definition and fine criteria, and can be reduced by consensus of definition and standardisation of grading criteria.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Factors to improve the interobserver agreement for gastric atrophy and intestinal metaplasia: consensus of definition and criteria
- Date Crossref
- 19/01/2018
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Chonnam National University Hospital Department of Pathology pays non établi dans la noticeÉtablissement de santé
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National Cancer Center Biometric Research Branch pays non établi dans la noticeÉtablissement de santé
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The Catholic University of Korea Uijeongbu St. Mary's Hospital Department of Pathology pays non établi dans la noticeÉtablissement de santé
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Catholic University of Korea pays non établi dans la noticeUniversité ou école supérieure
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Chung-Ang University pays non établi dans la noticeUniversité ou école supérieure
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Kyungpook National University Hospital pays non établi dans la noticeÉtablissement de santé
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Kyungpook National University Chilgok Hospital pays non établi dans la noticeÉtablissement de santé
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Pusan National University pays non établi dans la noticeUniversité ou école supérieure
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Center for Gastric Cancer pays non établi dans la noticeInstitution
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Deparment of Pathology School of Medicine Chung‐Ang University Seoul South Korea Deparment of Pathology pays non établi dans la noticeUniversité ou école supérieure
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Research Institute Biometric Research Branch pays non établi dans la noticeStructure de recherche
Department of Pathology — Chonnam National University Hospital, Biometric Research Branch — National Cancer Center et Department of Pathology — The Catholic University of Korea Uijeongbu St. Mary's Hospital, avec 8 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.