P1620TRPG/TAPSE a novel parameter for stepwise echocardiographic risk stratification in normotensive patients with acute pulmonary embolism

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Background: Patients with intermediate-risk acute pulmonary embolism (APE) are very heterogeneous group with early mortality between 2–15%. More of this subjects hemodynamically stabilized during treatment but in some of them clinical deterioration is observed. It was reported that tricuspid annulus plane systolic excursion (TAPSE) can be used for identification of a very low-risk group. Tricuspid regurgitation peak gradient (TRPG) can also be used for risk stratification. Purpose: The aim of this study was to analyse the prognostic value of a new echo parameter TRPG/TAPSE for prediction of APE related 30 days mortality or need for rescue thrombolysis in initially normotensive APE patients. Methods: The study group consist of 400 non high risk APE patients (191 men, 209 women, age:63.1±18.9). Echo examination was performed with a Philips iE 33 as soon as possible. RV function was assessed by TAPSE and TRPG measurement. The TRPG/TAPSE parameter was calculated. The clinical endpoint (CE) was a combination of 30-day APE-related mortality and/or rescue thrombolysis.

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