Cytotrophoblastic changes in PIH

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Introduction: Placenta is related to mother and fetus by indirect interaction with maternal blood that spruts out of uteroplacental vessels. Preeclampsia and intrauterine fetal growth retardation are the disorders which provide information by the study of placental bed. Aims: To studychanges in cytotrophoblstic cells of placenta in normotensive and pregnancy induced hypertensive parturients. Materials and Method: This study was conducted in the Department of Anatomy and Pathology, Government Medical College, Patiala. The placentae were collected from labour room, Rajindra Hospital, Patiala which include seventy five cases of pregnancy induced hypertension and twenty five cases of normotensive pregnancies. An attempt was made to find out changes in histological features of placentae of pregnancy induced hypertensive cases and compare it with the normotensive placentae. Results: Histopathological study showed significant significant paucity of CTB proliferation in hypertensive group. Conclusion: Histological changes in placente associated with PIH are due to occlusion of the uteroplacental vasculature and thusl mortality and morbidity associated with this condition is probably related to alterations in the uteroplacental flow. Keywords: Placenta, Cytotrophoblast, Syncytium

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