Front Cover: Multiplexing N‐glycan analysis by DNA analyzer

Résumé fourni par la source

Electrophoresis 2017, 38, 1788–1799. DOI: 10.1002/elps.201600404 The front cover picture shows a rapid and accurate method for analysis of glycans. Magnetic beads were applied to capture released N-glycans and remove excess dye (left). The bottom picture illustrates the individual exoglycosidase treatments to confirm glycan terminal monosaccharides. In the center, a multi-capillary array is used to analyze fluorescently labeled samples. IgG glycans separated by a multi-capillary system using different dyes are shown on the right. Data was annotated using three-dimensional mapping of glycan standards with three fluorescent dyes (top). The present method has demonstrated its fast, simple and easy-to-use design to meet the needs of high throughput glycan analysis.

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