Agricultural Pesticide Exposure and Congenital Abnormalities (CA) in Mexico: A Systematic Review

Résumé fourni par la source

TPS 633: Health effects of pesticides, Johan Friso Foyer, Floor 1, August 27, 2019, 3:00 PM - 4:30 PM Agricultural Pesticide Exposure and Congenital Abnormalities (CA) in Mexico: A Systematic Review Authors: Brenda M. Trejo1 and Melissa J. Perry2 Affiliation: 1Department of Environmental Health, Boston University, Boston, MA, USA 2Department of Environmental and Occupational Health, Milken Institute School of Public Health, George Washington University, Washington DC, USA Background: Pesticide exposure has been associated with congenital abnormalities (CA), which are a public health concern in Mexico. Objective: This systematic review identified literature that addressed the relationship between parental exposure to agricultural pesticides via agricultural work and CA among infants of Mexican parents. The systematic literature review sought to communicate the findings of the association, identify strengths and limitations, and make recommendations for further research. Methods: Articles were identified using PubMed with secondary searches of Scopus, PubMed Central, ProQuest Environmental Science, Academic Search Complete, Popline and hand search of references of the identified articles. Results: Seven studies were identified that investigated the association between agricultural pesticide exposure and CA in Mexico. Six studies observed a positive association; one study found no association. Five studies investigated exposure to specific pesticide(s) and two investigated general pesticide exposure. Five studies relied on self-reporting for ascertainment of exposure and/or outcome. Two studies used more objective methods, such as biomarkers and clinical diagnosis for both the exposure and outcome of interest. Five studies investigated specific CA; two studies investigated CA generally. Conclusion: The reviewed literature supported the positive association between pesticides and CA while demonstrating a need for improved exposure and outcome ascertainment.

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