Characteristics of Fentanyl Overdose — Massachusetts, 2014–2016
Rattachement africain : us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Opioid overdose deaths in Massachusetts increased 150% from 2012 to 2015 (1). The proportion of opioid overdose deaths in the state involving fentanyl, a synthetic, short-acting opioid with 50-100 times the potency of morphine, increased from 32% during 2013-2014 to 74% in the first half of 2016 (1-3). In April 2015, the Drug Enforcement Agency (DEA) and CDC reported an increase in law enforcement fentanyl seizures in Massachusetts, much of which was believed to be illicitly manufactured fentanyl (IMF) (4). To guide overdose prevention and response activities, in April 2016, the Massachusetts Department of Public Health and the Office of the Chief Medical Examiner collaborated with CDC to investigate the characteristics of fentanyl overdose in three Massachusetts counties with high opioid overdose death rates. In these counties, medical examiner charts of opioid overdose decedents who died during October 1, 2014-March 31, 2015 were reviewed, and during April 2016, interviews were conducted with persons who used illicit opioids and witnessed or experienced an opioid overdose. Approximately two thirds of opioid overdose decedents tested positive for fentanyl on postmortem toxicology. Evidence for rapid progression of fentanyl overdose was common among both fatal and nonfatal overdoses. A majority of interview respondents reported successfully using multiple doses of naloxone, the antidote to opioid overdose, to reverse suspected fentanyl overdoses. Expanding and enhancing existing opioid overdose education and prevention programs to include fentanyl-specific messaging and practices could help public health authorities mitigate adverse effects associated with overdoses, especially in communities affected by IMF.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Characteristics of Fentanyl Overdose — Massachusetts, 2014–2016
- Date Crossref
- 14/04/2017
- Éditeur
- Centers for Disease Control MMWR Office
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Harvard University Press pays non établi dans la noticeInstitution
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Substance Abuse and Mental Health Services Administration pays non établi dans la noticeOrganisme public
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Centers for Disease Control and Prevention pays non établi dans la noticeOrganisme public
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University of Massachusetts Boston pays non établi dans la noticeUniversité ou école supérieure
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Greater Lawrence Family Health Center pays non établi dans la noticeÉtablissement de santé
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Office of Chief Medical Examiner pays non établi dans la noticeOrganisme public
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SAMHSA pays non établi dans la noticeInstitution
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Ctr Dis Control & Prevent pays non établi dans la noticeInstitution
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CHIRP pays non établi dans la noticeInstitution
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Univ of Massachusetts Boston pays non établi dans la noticeUniversité ou école supérieure
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Lawrence Family Med Residency pays non établi dans la noticeInstitution
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Massachusetts Off Chief Med Examiner pays non établi dans la noticeInstitution
Harvard University Press, Substance Abuse and Mental Health Services Administration et Centers for Disease Control and Prevention, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.