The role of the pangenome concept in selecting new starter cultures

Le résumé fourni par la source

In the last few years, a pangenomic approach has been proposed for the characterization of bacteria and to improve industrial starter cultures and the functionality of probiotics. This approach allows information to be provided that can be used for strain screening, improvement, safety assessments and process improvements. It offers the opportunity to compare the genetic repertoire of different species and genera, pathogens and non-pathogens, and to formulate new hypotheses in commensal, probiotic and pathogenic relationships with the host. In particular, pangenomic studies allow for identification of the common genes that are shared and, possibly, encode those phenotypical features. Several online pangenome sequence analysis programs have been designed, such as Panseq, PGAT and PANCGH, in order to make a pangenome analysis more useful for one bacterial population.

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