MP655PERITONEAL (PD) OR HEMODIALYSIS (HD) - DIALYSIS VINTAGE DEPENDENT COMPARISON OF BODY COMPOSITION, HYDRATION AND NUTRITION

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Introduction and Aims: Body mass decomposition in patients (pts) on maintenance dialysis (MD) is influenced by uremia-induced malnutrition, and deregulation of tissue metabolism with muscle protein breakdown, and overhydration state. Here we compared-according to dialysis vintage (DV) - body composition, hydration and nutritional state in MD pts treated by PD and HD and links to cardiovascular (CV) and all-cause mortality. Methods: 301 prevalent MD pts on HD (n=301) and PD (n=58) were divided into 3 subgroups depending on DV: <2 years HD (n=41) and PD (n=28), 2-4 years HD (n=111) and PD (n=17), > 4 years HD (n=149) and PD (n=13). All pts underwent whole-body multiple-frequency bioimpedance analysis (BIA; by BCM, Fresenius) yielding indices overhydration to total body weight ratio (OH), Lean Tissue Mass (LTM) and Fat Tissue Mass (FAT). Other measurements included body mass index (BMI), residual daily diuresis (DD), subjective global assessment (SGA) of nutritional state and circulating markers hemoglobin (Hb), albumin (alb), C-reactive protein (CRP) and total cholesterol (Tchol). Pts were followed up for 24 months.

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