Accès ouvert déclaré 2016 article

Association of Major Depression With Risk of Ischemic Heart Disease in a Mega‐Cohort of Chinese Adults: The China Kadoorie Biobank Study

Na Liu, Xiong‐Fei Pan, Canqing Yu, Jun Lv, Yu Guo, Zheng Bian, Ling Yang, Yiping Chen, Tangchun Wu, Zhengming Chen, An Pan, Liming Li, Junshi Chen, Rory Collins, Richard Peto, Garry Lancaster, Xiaoming Yang, Alex Williams, Margaret Smith, Yu‐Mei Chang, Guoqing Zhao, Lixue Wu, Can Hou, Zengchang Pang, Shaojie Wang, Yun Zhang, Kui Zhang, Silu Liu, Zhonghou Zhao, Shumei Liu, Zhigang Pang, Weijia Feng, Shuling Wu, Liqiu Yang, Huili Han, Hui He, Xian-hai Pan, Shanqing Wang, Hongmei Wang, Chunxing Chen, Shuxiong Lin, Xiao‐shu Hu, Minghao Zhou, Ming Wu, Yeyuan Wang, Yihe Hu, Liangcai Ma, Renxian Zhou, Guanqun Xu, Baiqing Dong, Naying Chen, Ying Huang, Mingqiang Li, Jinhuai Meng, Zhigao Gan, Jiujiu Xu, Yun Liu, Xianping Wu, Yali Gao, Ningmei Zhang, Guojin Luo, Xiangsan Que, Xiaofang Chen, Pengfei Ge, Jian He, Xiaolan Ren, Hui Zhang, Enke Mao, Guanzhong Li, Zhongxiao Li, Jun He, Guohua Liu, Baoyu Zhu, Gang Zhou, Shixian Feng, Yulian Gao, Tianyou He, Li Jiang, Jianhua Qin, Huarong Sun, Liqun Liu, Min Yu, Yaping Chen, Zhixiang Hu, Jianjin Hu, Yijian Qian, Zhiying Wu, Lingli Chen, Wen Liu, Guangchun Li, Huilin Liu, Xiangquan Long, Youping Xiong, Zhongwen Tan, Xuqiu Xie, Yunfang Peng

41Citations signalées, ce qui n’est pas une note de qualité

6Institutions déclarées

2Pays d’affiliation déclarés

Rattachement africain : cn, gb. Niveau de preuve : code pays fourni par la source.

Le résumé fourni par la source

BACKGROUND: Increasing evidence has suggested that major depression (MD) is associated with an increased risk of ischemic heart disease (IHD). We examined this association in Chinese adults using data from the China Kadoorie Biobank study. METHODS AND RESULTS: Over 0.5 million adults aged 30 to 79 years were followed from baseline interview (2004-2008) until December 31, 2013. Past year MD was measured with the modified Chinese version of Composite International Diagnostic Interview-Short Form at baseline. Incident IHD cases were identified through linkage to related medical databases, and defined as having International Statistical Classification of Diseases and Related Health Problems 10th Revision codes of I20 to I25. Cox proportional hazards regression models were used to estimate hazard ratios and 95% CIs for the MD-IHD association with adjustment for sociodemographic variables and established cardiovascular risk factors. During 3 423 542 person-years of follow-up, 24 705 incident IHD cases were documented. Higher IHD incidence was observed in participants with MD compared with those without (8.76 versus 7.21 per 1000 person-years), and the multivariable-adjusted hazard ratio was 1.32 (95% CI 1.15-1.53). Geographic location modified the association (P for interaction=0.005), and a positive association was observed in urban residents (hazard ratio 1.72; 95% CI 1.39-2.14) but not rural residents (1.13; 0.93-1.37). Compared with participants without depressive symptoms, the hazard ratio (95% CI) of IHD was 1.13 (1.04-1.23) for those with depressive symptoms only and 1.33 (1.15-1.53) for those with MD. CONCLUSIONS: Past year major depression was associated with an increased risk of IHD in Chinese adults, independent of other major cardiovascular risk factors.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.

Le contrôle bibliographique ouvert

DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.

Titre Crossref: Association of Major Depression With Risk of Ischemic Heart Disease in a Mega‐Cohort of Chinese Adults: The China Kadoorie Biobank Study
Date Crossref: 01/12/2016
Éditeur: Ovid Technologies (Wolters Kluwer Health)
Type: journal-article

Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.

Les institutions déclarées

Huazhong University of Science and Technology Nanjing Medical University Peking University Academy of Medical Sciences Chinese Academy of Medical Sciences & Peking Union Medical College University of Oxford

Une affiliation ne permet pas de déduire la nationalité d’un auteur.

Les sujets associés

Cardiac Health and Mental HealthCardiovascular Health and Risk FactorsTryptophan and brain disorders

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