SPRYSEC Effectors: A Versatile Protein-Binding Platform to Disrupt Plant Innate Immunity
Rattachement africain : nl, ro. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Persistent infections by sedentary plant-parasitic nematodes are a major threat to important food crops all over the world. These round worms manipulate host plant cell morphology and physiology to establish sophisticated feeding structures. Key modifications to plant cells during their transition into feeding structures are largely attributed to the activity of effectors secreted by the nematodes. The SPRYSEC effectors were initially identified in the potato cyst nematodes Globodera rostochiensis and G. pallida, and are characterized by a single SPRY domain, a non-catalytic domain present in modular proteins with different functions. The SPRY domain is wide-spread among eukaryotes and thought to be involved in mediating protein-protein interactions. Thus far, the SPRY domain is only reported as a functional domain in effectors of plant-parasitic nematodes, but not of other plant pathogens. SPRYSEC effectors have been implicated in both suppression and activation of plant immunity, but other possible roles in nematode virulence remain undefined. Here, we review the latest reports on the structure, function, and sequence diversity of SPRYSEC effectors, which provide support for a model featuring these effectors as a versatile protein-binding platform for the nematodes to target a wide range of host proteins during parasitism.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- SPRYSEC Effectors: A Versatile Protein-Binding Platform to Disrupt Plant Innate Immunity
- Date Crossref
- 20/10/2016
- Éditeur
- Frontiers Media SA
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Wageningen University & Research Laboratory of Nematology pays non établi dans la noticeUniversité ou école supérieure
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Academia Oamenilor de Știință din România pays non établi dans la noticeStructure de recherche
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Institute of Biochemistry Department of Bioinformatics and Structural Biochemistry pays non établi dans la noticeUniversité ou école supérieure
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Romanian Academy pays non établi dans la noticeInstitution
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Wageningen University Wageningen Laboratory of Nematology pays non établi dans la noticeUniversité ou école supérieure
Laboratory of Nematology — Wageningen University & Research, Academia Oamenilor de Știință din România et Department of Bioinformatics and Structural Biochemistry — Institute of Biochemistry, avec 2 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.