The Role of Exercise in Chemotherapy-Induced Peripheral Neuropathy

Le résumé fourni par la source

Chemotherapy-induced peripheral neuropathy (CIPN) is the most common neurological side effect of chemotherapy and is characterized by damage to the nervous system that is a direct result of the medications associated with chemotherapy. Often, this damage to the central nervous system pain pathways results in neuropathic pain described as burning, paroxysmal, stabbing, or elective shock-like and accompanied by pins-and-needles sensations and itching. The presence and severity of neuropathic pain is often shown to be associated with impairments in walking, general activities, sleep, work, mood, enjoyment of life, and relationships with others. Treatment of neuropathic pain due to CIPN often requires a multidisciplinary approach due to the broad variety of symptoms and their negative impact on quality of life. To provide treatment strategies that are effective for patients, they should include a combination of pharmacological agents and exercise rehabilitation. Exercise rehabilitation programs should be designed in order to help patients familiarize themselves to changes in physical functioning. The goals of the program should target three main areas: maximize functional capacities, prolong or maintain independent function, and improve quality of life.

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